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Protoflow Vitamin E and Prostate Cancer Risk
Protoflow has 13 mg of vitamin E per serving, 87% of the daily value. The SELECT trial found that men who took 400 IU of vitamin E alone had a higher rate of prostate cancer than placebo. Protoflow's dose is far lower, but men should count all sources and tell their doctor.
Written by the Protoflow label teamUpdated · 4 min read
Amount01
How much vitamin E is in Protoflow?
13 mg per serving, which is 87% of the 15 mg daily value.
The label does not say if it is natural or synthetic vitamin E. In IU, 13 mg of natural vitamin E is about 19 IU and of synthetic about 29 IU. That is modest compared with the 400 IU used in the trial below, and it is near what a normal diet and a multivitamin might give.
The trial02
What was the SELECT trial?
A large US trial that tested selenium and vitamin E for preventing prostate cancer in more than 35,000 men.
It found no benefit from either, and after longer follow-up, men who took 400 IU of vitamin E daily alone had a higher rate of prostate cancer than those on placebo (NIH ODS, Vitamin E). NIH reports the finding on its vitamin E fact sheet. The trial did not test a blend, and it did not test low doses, so it does not say Protoflow raises the risk.
At a glance03
How does the trial dose compare?
| Item | Amount |
|---|---|
| Daily value | 15 mg |
| Protoflow per serving | 13 mg |
| SELECT trial dose | 400 IU (about 180 mg of natural form) |
| Adult upper limit | 1,000 mg (NIH ODS, Vitamin E) |
Meaning04
What does that mean for you?
It means large vitamin E supplements are not a good idea for prostate health, and low amounts are less clear.
The trial is a reason to avoid high-dose vitamin E for cancer prevention. It is not a reason to panic over a dose near the daily value. The risk lies in stacking: a multivitamin, a separate vitamin E capsule and a blend can add up to well above 13 mg without you noticing.
Stacking05
How do you count your total?
- List every product with vitamin E on the label
- Convert IU to mg, or the other way, using the label
- Add the amounts from food and drink only roughly
- Show the total to a pharmacist
If the total comes to more than a few times the daily value, ask whether you need it all.
Bleeding06
What about bleeding?
High doses of vitamin E may reduce clotting, which adds to the ginkgo caution in the blend.
NIH notes that vitamin E can increase bleeding risk in high doses and with blood thinners (NIH ODS, Vitamin E). Protoflow's dose is modest, but the combination with ginkgo is the thing to raise with a prescriber. Tell the surgeon, too, before any procedure.
Never stop a drug for this. Tell each prescriber about the capsules.
Screening07
Does this change PSA testing?
No: vitamin E is not known to change PSA, and screening decisions are made between you and your doctor.
The NCI explains that PSA testing has benefits and harms, and that there is no standard cutoff (NCI, PSA Test). If you have a family history, are Black, or are over 50, ask when to talk about testing. The decision does not depend on your vitamin choices.
Prevention08
What does reduce risk or find problems early?
Not smoking, staying active, keeping a healthy weight and discussing screening with your doctor.
No supplement has been proven to prevent prostate cancer. Large trials of selenium, vitamin E and others have been disappointing. A doctor can discuss your risk and tell you about tests. Nothing here replaces that conversation, and nothing in Protoflow is claimed to prevent cancer.
Bottom line09
What is the bottom line on vitamin E?
At 13 mg it is a modest dose, and the trial concern applies to much higher amounts.
Count your total, tell your doctor about the product and keep prescribed medicine. If you are worried, ask whether you need any vitamin E supplement at all.
FAQ10
Questions on this topic
Does vitamin E cause prostate cancer?
The SELECT trial found more prostate cancer in men taking 400 IU alone. A 13 mg dose is far lower, and cause is not shown for it.
Is 13 mg of vitamin E safe?
It is below the 1,000 mg upper limit. Count other sources and ask about bleeding if you take blood thinners.
Should I avoid vitamin E if I have prostate problems?
Ask your doctor. Avoid high doses without advice.
Does Protoflow prevent prostate cancer?
No. The label makes no such claim, and no supplement is proven to prevent it.
Who wrote this11
Written and reviewed by
Pages built from the label, the sales page and linked NIH, FDA, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by a USA authorized retailer of Protoflow, not by the manufacturer or the label distributor. Buying through our order links earns us money.
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